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KMID : 1141920230390040315
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Annals of Coloproctology
2023 Volume.39 No. 4 p.315 ~ p.325
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Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery
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Masahiro Kataoka
Kuniyuki Gomi
Ken Ichioka
Takuya Iguchi
Tomoki Shirota
Arano Makino
Ko Shimada
Kiyotomi Maruyama
Motohiro Mihara
Shoji Kajikawa
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Abstract
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Purpose : C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC).
Methods : Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (72 patients per group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching.
Results : The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed.
Conclusion : In patients with CRC, CAR of POD 7 was a significant prognostic factor.
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KEYWORD
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C-reactive protein, Albumins, Colorectal neoplasms, Laparoscopy, Prognosis
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